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Proteintech
UROD Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
15547-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
UROD Fusion Protein Ag7905 (1-367 aa encoded by BC001778)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MEANGLGPQ GFPELKNDTF LRAAWGEETD YTPVWCMRQA GRYLPEFRET RAAQDFFSTC RSPEACCELT LQPLRRFPLD AAIIFSDILV VPQALGMEVT MVPGKGPSFP EPLREEQDLE RLRDPEVVAS ELGYVFQAIT LTRQRLAGRV PLIGFAGAPW TLMTYMVEGG GSSTMAQAKR WLYQRPQASH QLLRILTDAL VPYLVGQVVA GAQALQLFES HAGHLGPQLF NKFALPYIRD VAKQVKARLR EAGLAPVPMI IFAKDGHFAL EELAQAGYEV VGLDWTVAPK KARECVGKTV TLQVNLDPCA LYASEEEIGQ LVKQMLDDFG PHRYIANLGH GLYPDMDPEH VGAFVDAVHK HSRLLRQN (1-367 aa encoded by BC001778)
Target Information
This gene encodes the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: porphyrinogen carboxylase; unnamed protein product; UPD; URO D; URO-D; UROD; uroporphyrinogen decarboxylase (EC 4.1.1.37); uroporphyrinogen III decarboxylase
Gene Aliases: PCT; porphyrinogen carboxy-lyase; UPD; Uro-d
UniProt ID: (Human) P06132, (Mouse) P70697
Entrez Gene ID: (Human) 7389, (Mouse) 22275, (Rat) 29421
porphyrin-containing compound metabolic process
porphyrin-containing compound biosynthetic process
heme biosynthetic process
heme a biosynthetic process
heme B biosynthetic process
porphyrin-containing compound catabolic process
cell proliferation
heme metabolic process
uroporphyrinogen III metabolic process
liver development
response to iron ion
response to amine
response to estradiol
response to ethanol
response to mercury ion
response to methylmercury
response to fungicide
cellular response to arsenic-containing substance
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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