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Product Details
22327-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
USF1 Fusion Protein Ag17789 (1-310 aa encoded by BC035505)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKGQQKTAE TEEGTVQIQE GAVATGEDPT SVAIASIQSA ATFPDPNVKY VFRTENGGQV MYRVIQVSEG QLDGQTEGTG AISGYPATQS MTQAVIQGAF TSDDAVDTEG TAAETHYTYF PSTAVGDGAG GTTSGSTAAV VTTQGSEALL GQATPPGTGQ FFVMMSPQEV LQGGSQRSIA PRTHPYSPKS EAPRTTRDEK RRAQHNEVER RRRDKINNWI VQLSKIIPDC SMESTKSGQS KGGILSKACD YIQELRQSNH RLSEELQGLD QLQLDNDVLR QQVEDLKNKN LLLRAQLRHH GLEVVIKNDS N (1-310 aa encoded by BC035505)
Target Information
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: bHLHb11; Class B basic helix-loop-helix protein 11; Major late transcription factor 1; Upstream stimulatory factor 1; usf1-bd
Gene Aliases: BHLHB11; FCHL; FCHL1; HYPLIP1; MLTF; MLTFI; UEF; USF; USF1
UniProt ID: (Human) P22415
Entrez Gene ID: (Human) 7391
double-stranded DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
enzyme binding
protein kinase binding
protein homodimerization activity
histone deacetylase binding
bHLH transcription factor binding
sequence-specific DNA binding
protein heterodimerization activity
regulation of transcription from RNA polymerase II promoter by glucose
positive regulation of transcription from RNA polymerase II promoter by glucose
response to hypoxia
glucose metabolic process
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to UV
late viral transcription
cellular response to insulin stimulus
glucose homeostasis
positive regulation of transcription from RNA polymerase II promoter
carbon catabolite regulation of transcription
negative regulation of fibrinolysis
lipid homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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