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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • USH1C Antibodies

          Invitrogen

          USH1C Polyclonal Antibody

          View all (18) USH1C antibodies

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          Cite USH1C Polyclonal Antibody

          • Antibody Testing Data (1)
          USH1C Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          USH1C Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          USH1C Antibody (PA5-18253) in WB

          Western blot analysis of USH1C using USH1C Polyclonal Antibody (Product # PA5-18253) (0.1 µg/mL) in staining of HEK293 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          USH1C Antibody in Western Blot (WB)
          USH1C Polyclonal Antibody

          Product Details

          PA5-18253

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.1-0.3 µg/mL
          -

          Immunohistochemistry (IHC)

          10 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Goat / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide sequence (DRKVAREFRHKVD) corresponding to the N-terminus amino acids of USH1C (aa 2-15).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Purification

          Ammonium sulfate precipitation

          Storage buffer

          TBS, pH 7.3, with 0.5% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_10981632

          Product Specific Information

          This antibody is predicted to react with bovine, mouse and rat based on sequence homology.

          This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

          Target Information

          This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Antigen NY-CO-38/NY-CO-37; Autoimmune enteropathy-related antigen AIE-75; Harmonin; PDZ-73 protein; Protein PDZ-73; Renal carcinoma antigen NY-REN-3; Usher syndrome 1C (autosomal recessive, severe); Usher syndrome type-1C protein

          View more View less

          Gene Aliases: AIE-75; AIE75; DFNB18; DFNB18A; NY-CO-37; NY-CO-38; PDZ-45; PDZ-73; PDZ-73/NY-CO-38; PDZ73; PDZD7C; USH1C; ush1cpst

          View more View less

          UniProt ID: (Human) Q9Y6N9

          View more View less

          Entrez Gene ID: (Human) 10083

          View more View less

          Function(s)
          protein binding spectrin binding myosin tail binding actin filament binding cytoskeletal protein
          Process(es)
          G2/M transition of mitotic cell cycle sensory perception of sound cell differentiation regulation of microvillus length cellular protein complex assembly photoreceptor cell maintenance sensory perception of light stimulus equilibrioception protein localization to microvillus brush border assembly
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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