FIGURE: 1 / 7
Immunogen sequence: KFIPLYSKV QRPCTSTPMI DSFVRLMNEF TNMPVPPKPR QALGDKIVRD IRPGAAFEPT YIYRLLTVNK SSLSEKGRQE DAEEYLGFIL NGLHEEMLNL KKLLSPSNEK LTISNGPKNH SVNEEEQEEQ GEGSEDEWEQ VGPRNKTSVT RQADFVQTPI TGIFGGHIRS VVYQQSSKES ATLQPFFTLQ LDIQSDKIRT VQDALESLVA RESVQGYTTK TKQEVEISRR VTLEKLPPVL VLHLKRFVYE KTGGCQKLIK NIEYPVDLEI SKELLSPGVK NKNFKCHRTY RLFAVVYHHG NSATGGHYTT DVFQIGLNGW LRIDDQTVKV INQYQVVKPT AERTAYLLYY RRVDLL (444-798 aa encoded by BC000263)
USP10, also known as ubiquitin specific peptidase 10, belongs to the ubiquitin-specific protease family of cysteine proteases. USP10 functions to catalyze the cleavage of ubiquitin from ubiquitin-conjugated protein substrates such as p53/TP53, SNX3 and CFTR. USP10 has been identified as a subunit of DNA-bound androgen receptor (AR) complexes and may play a role in the activity of the DNA-bound androgen receptor complex. USP10 also acts as an essential regulator of p53/TP53 stability and is thought to function as a tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Deubiquitinating enzyme 10; MGC2621; ubiquintin c-terminal hydrolase related polypeptide; Ubiquitin carboxyl-terminal hydrolase 10; ubiquitin specific protease 10; Ubiquitin thioesterase 10; ubiquitin thiolesterase 10; Ubiquitin-specific-processing protease 10
Gene Aliases: 2610014N07Rik; KIAA0190; mKIAA0190; Ode-1; UBPO; Uchrp; USP10