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Invitrogen
USP18 Polyclonal Antibody
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Product Details
PA5-42843
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human USP18 (aa 110-159).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: MQDSRQKAVR PLELAYCLQK CNVPLFVQHD AAQLYLKLWN LIKDQITDVH
Sequence homology: Cow: 79%; Dog: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 85%; Rabbit: 92%; Rat: 85%
Target Information
USP18, a member of the deubiquitinating protease family of enzymes, removes ubiquitin adducts from a broad range of protein substrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 43 kDa ISG15-specific protease; 43kDa interferon-induced protein; Em:AC008079.1; hUBP43; ISG15-specific-processing protease; ubiquitin specific protease 15; ubiquitin specific protease 18; Ubl carboxyl-terminal hydrolase 18; Ubl thioesterase 18; ubl thiolesterase 18; unnamed protein product; USP18
Gene Aliases: 1110058H21Rik; AW047653; ISG43; PTORCH2; Ubp15; UBP43; USP18
UniProt ID: (Human) Q9UMW8, (Mouse) Q9WTV6
Entrez Gene ID: (Human) 11274, (Mouse) 24110
thiol-dependent ubiquitin-specific protease activity
protein binding
peptidase activity
cysteine-type peptidase activity
hydrolase activity
ISG15-specific protease activity
binding, bridging
cysteine-type endopeptidase activity
pyroglutamyl-peptidase activity
thiol-dependent ubiquitinyl hydrolase activity
cysteine protease
proteolysis
response to bacterium
protein deubiquitination
regulation of protein stability
response to stilbenoid
regulation of inflammatory response
response to other organism
negative regulation of type I interferon-mediated signaling pathway
antiviral innate immune response
ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of proteasomal protein catabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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