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Product Details
17491-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
USP20 Fusion Protein Ag11590 (1-351 aa encoded by BC039593)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MGDSRDLCP HLDSIGEVTK EDLLLKSKGT CQSCGVTGPN LWACLQVACP YVGCGESFAD HSTIHAQAKK HNLTVNLTTF RLWCYACEKE VFLEQRLAAP LLGSSSKFSE QDSPPPSHPL KAVPIAVADE GESESEDDDL KPRGLTGMKN LGNSCYMNAA LQALSNCPPL TQFFLECGGL VRTDKKPALC KSYQKLVSEV WHKKRPSYVV PTSLSHGIKL VNPMFRGYAQ QDTQEFLRCL MDQLHEELKE PVVATVALTE ARDSDSSDTD EKREGDRSPS EDEFLSCDSS SDRGEGDGQG RGGGSSQAET ELLIPDEAGR AISEKERMKD RKFSWGQQRT NSEQVDEDAD VD (1-351 aa encoded by BC039593)
Target Information
SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Deubiquitinating enzyme 20; hVDU2; pVHL-interacting deubiquitinating enzyme 2; Ubiquitin carboxyl-terminal hydrolase 20; ubiquitin specific protease 20; Ubiquitin thioesterase 20; ubiquitin thiolesterase 20; Ubiquitin-specific-processing protease 20; VHL-interacting deubiquitinating enzyme 2
Gene Aliases: 1700055M05Rik; AI467231; hVDU2; KIAA1003; LSFR3A; USP20; VDU2
UniProt ID: (Human) Q9Y2K6, (Mouse) Q8C6M1
Entrez Gene ID: (Human) 10868, (Mouse) 74270, (Rat) 311856
G-protein coupled receptor binding
cysteine-type endopeptidase activity
thiol-dependent ubiquitin-specific protease activity
protein binding
zinc ion binding
peptidase activity
cysteine-type peptidase activity
hydrolase activity
thiol-dependent ubiquitinyl hydrolase activity
metal ion binding
cysteine protease
ubiquitin-dependent protein catabolic process
endocytosis
regulation of G-protein coupled receptor protein signaling pathway
protein deubiquitination
protein K63-linked deubiquitination
protein K48-linked deubiquitination
proteolysis
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of proteasomal protein catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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