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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | View 2 publications 2 publications |
Immunohistochemistry (IHC) |
- | View 2 publications 2 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
USP20 Fusion Protein Ag11590 (1-351 aa encoded by BC039593) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.25 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MGDSRDLCP HLDSIGEVTK EDLLLKSKGT CQSCGVTGPN LWACLQVACP YVGCGESFAD HSTIHAQAKK HNLTVNLTTF RLWCYACEKE VFLEQRLAAP LLGSSSKFSE QDSPPPSHPL KAVPIAVADE GESESEDDDL KPRGLTGMKN LGNSCYMNAA LQALSNCPPL TQFFLECGGL VRTDKKPALC KSYQKLVSEV WHKKRPSYVV PTSLSHGIKL VNPMFRGYAQ QDTQEFLRCL MDQLHEELKE PVVATVALTE ARDSDSSDTD EKREGDRSPS EDEFLSCDSS SDRGEGDGQG RGGGSSQAET ELLIPDEAGR AISEKERMKD RKFSWGQQRT NSEQVDEDAD VD (1-351 aa encoded by BC039593)
SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Deubiquitinating enzyme 20; hVDU2; pVHL-interacting deubiquitinating enzyme 2; Ubiquitin carboxyl-terminal hydrolase 20; ubiquitin specific protease 20; Ubiquitin thioesterase 20; ubiquitin thiolesterase 20; Ubiquitin-specific-processing protease 20; VHL-interacting deubiquitinating enzyme 2
Gene Aliases: 1700055M05Rik; AI467231; hVDU2; KIAA1003; LSFR3A; USP20; VDU2
UniProt ID: (Human) Q9Y2K6, (Mouse) Q8C6M1
Entrez Gene ID: (Human) 10868, (Mouse) 74270, (Rat) 311856
Molecular Function:
cysteine protease
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