Proteintech

USP20 Polyclonal Antibody

Product Image Gallery

USP20 Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 17491-1-AP (USP20 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

USP20 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human lung using 17491-1-AP (USP20 antibody) at dilution of 1:50 (under 10x lens).

USP20 Antibody in Immunoprecipitation (IP) — IP result of anti-USP20 (IP:17491-1-AP, 4ug; Detection:17491-1-AP 1:500) with HeLa cells lysate 1200ug.

Product Details

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1000

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

USP20 Fusion Protein Ag11590

Conjugate

Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Target Information

SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Deubiquitinating enzyme 20; hVDU2; pVHL-interacting deubiquitinating enzyme 2; Ubiquitin carboxyl-terminal hydrolase 20; ubiquitin specific protease 20; Ubiquitin thioesterase 20; ubiquitin thiolesterase 20; Ubiquitin-specific-processing protease 20; VHL-interacting deubiquitinating enzyme 2

Gene Aliases: 1700055M05Rik; AI467231; hVDU2; KIAA1003; LSFR3A; USP20; VDU2

UniProt ID: (Human) Q9Y2K6, (Mouse) Q8C6M1

Entrez Gene ID: (Human) 10868, (Mouse) 74270, (Rat) 311856

Function(s)

ubiquitin-dependent protein catabolic process endocytosis regulation of G-protein coupled receptor protein signaling pathway protein deubiquitination protein K63-linked deubiquitination protein K48-linked deubiquitination proteolysis proteasome-mediated ubiquitin-dependent protein catabolic process regulation of proteasomal protein catabolic process

Process(es)

G-protein coupled receptor binding cysteine-type endopeptidase activity thiol-dependent ubiquitin-specific protease activity protein binding zinc ion binding peptidase activity cysteine-type peptidase activity hydrolase activity thiol-dependent ubiquitinyl hydrolase activity metal ion binding