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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 262 and 503 of Human USP3|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30341 targets USP3 in WB applications and shows reactivity with Human samples.
The PA5-30341 immunogen is recombinant fragment corresponding to a region within amino acids 262 and 503 of Human USP3.
Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Deubiquitinating enzyme 3; SIH003; Ubiquitin carboxyl-terminal hydrolase 3; ubiquitin specific protease 3; Ubiquitin thioesterase 3; ubiquitin thiolesterase 3; Ubiquitin-specific-processing protease 3
SIH003; UBP; USP3