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          • Primary Antibodies ›
          • USP35 Antibodies

          Proteintech

          USP35 Polyclonal Antibody

          5 References
          View all (6) USP35 antibodies

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          Cite USP35 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          USP35 Antibody in Western Blot (WB)
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          USP35 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          USP35 Antibody (24559-1-AP) in WB

          A549 cells were subjected to SDS PAGE followed by western blot with 24559-1-AP ( USP35 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          USP35 Antibody in Western Blot (WB)
          USP35 Polyclonal Antibody

          Product Details

          24559-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          View 2 publications 2 publications

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunoprecipitation (IP)

          -
          View 1 publication 1 publication

          Not applicable (N/A)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          USP35 Fusion Protein Ag20002 (1-342 aa encoded by BC131489)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.29 mg/mL

          Amount

          43.5 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MPGLRRRAS WRVSIPGSWP SQTRARLVSS TWATHAMSTA SFRPYSWRLS SFRHCVLRLT ENNSQPLMTK LQWLFGFLEH SQRPAISPEN FLSASWTPWF SPGTQQDCSE YLKYLLDRLH EEEKTGTRIC QKLKQSSSPS PPEEPPAPSS TSVEKMFGGK IVTRICCLCC LNVSSREEAF TDLSLAFPPP ERCRRRRLGS VMRPTEDITA RELPPPTSAQ GPGRVGPRRQ RKHCITEDTP PTSLYIEGLD SKEAGGQSSQ EERIEREEEG KEERTEKEEV GEEEESTRGE GEREKEEEVE EEEEKVEKET EKEAEQEKEE DSLGAGTHPD AAIPSGERTC GSE (1-342 aa encoded by BC131489)

          Target Information

          p73 protein is a member of the p53 family of proteins. The tumor-suppressor protein p53 exhibits sequence specific DNA-binding, directly interacts with various cellular and viral proteins, and induces cell cycle arrest in response to DNA damage. In response to signals generated by a variety of genotoxic stresses, e.g, UV irradiation or DNA damage, p53 is expressed and undergoes post-translational modification that results in its accumulation in the nucleus. Activation of p53 leads to cell cycle arrest and in some cases to apoptosis, resulting in the inability of genetically damaged cells to proliferate. Thus, the p53-dependent pathways help to maintain genomic stability by eliminating damaged cells. The accumulation of high levels of p53 is a potential marker for malignancy.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Deubiquitinating enzyme 35; Ubiquitin carboxyl-terminal hydrolase 35; ubiquitin specific protease 35; Ubiquitin thioesterase 35; ubiquitin thiolesterase 35; Ubiquitin-specific-processing protease 35; unnamed protein product

          View more View less

          Gene Aliases: KIAA1372; USP34; USP35

          View more View less

          UniProt ID: (Human) Q9P2H5

          View more View less

          Entrez Gene ID: (Human) 57558

          View more View less

          Function(s)
          thiol-dependent ubiquitin-specific protease activity peptidase activity cysteine-type peptidase activity hydrolase activity
          Process(es)
          proteolysis protein deubiquitination regulation of protein stability
          It has to be done as per old AB suggested Products section.

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