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Bethyl Laboratories
USP35 Polyclonal Antibody
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FIGURE: 1 / 1
USP35 Antibody (A302-289A) in IP
Detection of human USP35 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-USP35 antibody (Product # A302-289A) used for IP at 10 µg/mg lysate. USP35 was also immunoprecipitated by rabbit anti-USP35 antibody A302-290A, which recognizes a downstream epitope. For blotting immunoprecipitated USP35, A302-290A was used at 1 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
Product Details
A302-289A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 875 and 925 of Human ubiquitin specific peptidase 35.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
p73 protein is a member of the p53 family of proteins. The tumor-suppressor protein p53 exhibits sequence specific DNA-binding, directly interacts with various cellular and viral proteins, and induces cell cycle arrest in response to DNA damage. In response to signals generated by a variety of genotoxic stresses, e.g, UV irradiation or DNA damage, p53 is expressed and undergoes post-translational modification that results in its accumulation in the nucleus. Activation of p53 leads to cell cycle arrest and in some cases to apoptosis, resulting in the inability of genetically damaged cells to proliferate. Thus, the p53-dependent pathways help to maintain genomic stability by eliminating damaged cells. The accumulation of high levels of p53 is a potential marker for malignancy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Deubiquitinating enzyme 35; Ubiquitin carboxyl-terminal hydrolase 35; ubiquitin specific protease 35; Ubiquitin thioesterase 35; ubiquitin thiolesterase 35; Ubiquitin-specific-processing protease 35
Gene Aliases: KIAA1372; USP34; USP35
UniProt ID: (Human) Q9P2H5
Entrez Gene ID: (Human) 57558
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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