Search
Proteintech
USP36 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
14783-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
USP36 Fusion Protein Ag6411 (1-285 aa encoded by BC038983)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Amount
25.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPIVDKLKE ALKPGRKDSA DDGELGKLLA SSAKKVLLQK IEFEPASKSF SYQLEALKSK YVLLNPKTEG ASRHKSGDDP PARRQGSEHT YESCGDGVPA PQKVLFPTER LSLRWERVFR VGAGLHNLGN TCFLNATIQC LTYTPPLANY LLSKEHARSC HQGSFCMLCV MQNHIVQAFA NSGNAIKPVS FIRDLKKIAR HFRFGNQEDA HEFLRYTIDA MQKACLNGCA KCVLPHPPSQ GFGHLFYMVA AEHSYGNSQP GTFLPRLPLG RRGRICLWVL KLLEPK (1-285 aa encoded by B C038983)
Target Information
May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Deubiquitinating enzyme 36; Ubiquitin carboxyl-terminal hydrolase 36; ubiquitin specific protease 36; Ubiquitin thioesterase 36; ubiquitin thiolesterase 36; Ubiquitin-specific-processing protease 36; unnamed protein product
Gene Aliases: 2700002L06Rik; DUB1; KIAA1453; mKIAA1453; USP36
UniProt ID: (Human) Q9P275, (Mouse) B1AQJ2
Entrez Gene ID: (Human) 57602, (Mouse) 72344
RNA binding
thiol-dependent ubiquitin-specific protease activity
protein binding
peptidase activity
cysteine-type peptidase activity
transferase activity
hydrolase activity
histone H2B deubiquitinase activity
Lys48-specific deubiquitinase activity
cysteine-type endopeptidase activity
thiol-dependent ubiquitinyl hydrolase activity
poly(A) RNA binding
cysteine protease
chromatin organization
chromatin remodeling
proteolysis
nucleolus organization
negative regulation of macroautophagy
protein deubiquitination
regulation of protein stability
regulation of apoptotic process
protein stabilization
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
regulation of rRNA processing
ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of proteasomal protein catabolic process
regulation of mitophagy
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support