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Proteintech
USP36 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
14783-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
USP36 Fusion Protein Ag6411 (1-285 aa encoded by BC038983)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.17 mg/mL
Amount
25.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPIVDKLKE ALKPGRKDSA DDGELGKLLA SSAKKVLLQK IEFEPASKSF SYQLEALKSK YVLLNPKTEG ASRHKSGDDP PARRQGSEHT YESCGDGVPA PQKVLFPTER LSLRWERVFR VGAGLHNLGN TCFLNATIQC LTYTPPLANY LLSKEHARSC HQGSFCMLCV MQNHIVQAFA NSGNAIKPVS FIRDLKKIAR HFRFGNQEDA HEFLRYTIDA MQKACLNGCA KCVLPHPPSQ GFGHLFYMVA AEHSYGNSQP GTFLPRLPLG RRGRICLWVL KLLEPK (1-285 aa encoded by B C038983)
Target Information
May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: deubiquitinating enzyme 36; ubiquitin specific protease 36; ubiquitin thioesterase 36; ubiquitin-specific-processing protease 36; unnamed protein product
Gene Aliases: 2700002L06Rik; DUB1; mKIAA1453
UniProt ID: (Human) Q9P275, (Mouse) B1AQJ2
Entrez Gene ID: (Human) 57602, (Mouse) 72344
chromatin organization
chromatin remodeling
nucleolus organization
negative regulation of macroautophagy
protein deubiquitination
regulation of protein stability
regulation of apoptotic process
protein stabilization
regulation of mitophagy
positive regulation of establishment of protein localization to mitochondrion
regulation of rRNA processing
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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