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May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Deubiquitinating enzyme 36; Ubiquitin carboxyl-terminal hydrolase 36; ubiquitin specific protease 36; Ubiquitin thioesterase 36; ubiquitin thiolesterase 36; Ubiquitin-specific-processing protease 36
Gene Aliases: 2700002L06Rik; DUB1; KIAA1453; mKIAA1453; USP36
UniProt ID: (Human) Q9P275, (Mouse) B1AQJ2
Entrez Gene ID: (Human) 57602, (Mouse) 72344, (Rat) 303700
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