Immunogen sequence: QEKPNTTVQV PAFLQELVDR DNSKFEEWCI EMAEMRKQSV DKGKAKHEEV KELYQRLPAG AEPYEFVSLE WLQKWLDEST PTKPIDNHAC LCSHDKLHPD KISIMKRISE YAADIFYSRY GGGPRLTVKA LCKECVV
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 94%.
USP48 is a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
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Protein Aliases: Deubiquitinating enzyme 48; Synaptic ubiquitin-specific protease; synUSP; Ubiquitin carboxyl-terminal hydrolase 48; ubiquitin specific protease 31; ubiquitin specific protease 48; Ubiquitin thioesterase 48; ubiquitin thiolesterase 48; Ubiquitin-specific peptidase 48; Ubiquitin-specific protease 48; Ubiquitin-specific-processing protease 48
Gene Aliases: 2810449C13Rik; AI115503; BC021769; D330022K21Rik; Kiaa4202; RAP1GA1; synUSP; USP31; USP48