Recommended positive controls: 293T, A431, Jurkat.
Predicted reactivity: Mouse (94%), Rat (93%), Chicken (84%), Rhesus Monkey (99%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Related to the N-terminus of tre; RN-tre; USP6 N-terminal-like protein
Gene Aliases: KIAA0019; RNTRE; TRE2NL; USP6NL; USP6NL-IT1
UniProt ID: (Human) Q92738
Entrez Gene ID: (Human) 9712