Search
Invitrogen
UTS2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
{{$ctrl.translations['antibody.pdp.skuNotes.additionalInformation']}}:
FIGURE: 1 / 2
UTS2 Antibody (PA5-102735) in IHC (P)
Immunohistochemistry analysis of UTS2 in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with UTS2 polyclonal antibody (Product # PA5-102735) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-102735
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human UTS2(Accession O95399), corresponding to amino acid residues Q88-V124.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total UTS2.
Target Information
Urotensin II is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: prepro U-II; UII; urocortin 2; urotensin II
Gene Aliases: PRO1068; U-II; UCN2; UII
UniProt ID: (Human) O95399, (Rat) Q9QZQ4
Entrez Gene ID: (Human) 10911, (Rat) 29180
response to hypoxia
negative regulation of glomerular filtration
positive regulation of cytosolic calcium ion concentration
regulation of blood pressure
response to xenobiotic stimulus
negative regulation of heart rate
positive regulation of heart rate
positive regulation of fibroblast migration
positive regulation of circadian sleep/wake cycle, wakefulness
positive regulation of synaptic transmission, cholinergic
positive regulation of collagen biosynthetic process
response to testosterone
negative regulation of urine volume
positive regulation of cell differentiation
positive regulation of angiogenesis
negative regulation of blood pressure
positive regulation of blood pressure
positive regulation of circadian sleep/wake cycle, REM sleep
negative regulation of insulin secretion
positive regulation of fibroblast proliferation
regulation of blood vessel diameter
muscle contraction
signal transduction
chemical synaptic transmission
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support