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Ube2L3 Polyclonal Antibody
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Product Details
BS-8350R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Ube2L3, amino acids 81-154.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E2 ubiquitin-conjugating enzyme L3; L-UBC; UbcH7; UbcM4; UBE2L3; Ubiquitin carrier protein L3; ubiquitin conjugating enzyme; ubiquitin conjugating enzyme E2L 3; ubiquitin-conjugating enzyme 7; Ubiquitin-conjugating enzyme E2 L3; Ubiquitin-conjugating enzyme E2-F1; ubiquitin-conjugating enzyme UBCH7; Ubiquitin-protein ligase L3; unnamed protein product
Gene Aliases: C79827; E2-F1; L-UBC; UBCE7; UBCH7; UbcM4; UBE2L3
UniProt ID: (Human) P68036, (Mouse) P68037
Entrez Gene ID: (Human) 7332, (Rat) 363836, (Mouse) 22195
nucleotide binding
transcription coactivator activity
RNA binding
ubiquitin-protein transferase activity
protein binding
ATP binding
transferase activity
ubiquitin-like protein transferase activity
enzyme binding
ubiquitin protein ligase binding
ubiquitin conjugating enzyme activity
ubiquitin-protein transferase activator activity
ligase activity
poly(A) RNA binding
ubiquitin-protein ligase
protein polyubiquitination
regulation of transcription, DNA-templated
ubiquitin-dependent protein catabolic process
cell proliferation
protein ubiquitination
positive regulation of protein ubiquitination
protein modification by small protein conjugation
protein modification process
cell cycle phase transition
positive regulation of transcription, DNA-templated
protein K11-linked ubiquitination
cellular response to steroid hormone stimulus
cellular response to glucocorticoid stimulus
positive regulation of protein targeting to mitochondrion
metabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of ubiquitin-protein transferase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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