Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: A431, H1299, HeLa, HepG2.
Predicted reactivity: Mouse (91%), Rat (87%), Dog (94%), Chimpanzee (98%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Protein unc-18 homolog 2; Protein unc-18 homolog B; Syntaxin-binding protein 2; Unc-18B; Unc18-2
Gene Aliases: FHL5; Hunc18b; MUNC18-2; pp10122; STXBP2; UNC18-2; UNC18B
UniProt ID: (Human) Q15833
Entrez Gene ID: (Human) 6813
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