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Product Details
18113-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:20-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Uroguanylin Fusion Protein Ag12589 (24-112 aa encoded by BC093779) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.17 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: TQSVYIQYQ GFRVQLESMK KLSDLEAQWA PSPRLQAQSL LPAVCHHPAL PQDLQPVCAS QEASSIFKTL RTIANDDCEL CVNVACTGCL (24-112 aa encoded by BC093779)
Target Information
Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GCAP-II; granule cell antiserum positive 2; Guanylate cyclase activator 2B; guanylate cyclase activator 2b (retina); guanylate cyclase activator 2B (uroguanylin); Guanylate cyclase C-activating peptide 2; Guanylate cyclase C-activating peptide II; prepro-uroguanylin; UGN; Uroguanylin
Gene Aliases: AV066530; GCAP-II; Gcap2; GUCA2B; UGN
UniProt ID: (Human) Q16661, (Mouse) O09051, (Rat) P70668
Entrez Gene ID: (Human) 2981, (Mouse) 14916, (Rat) 64055
Molecular Function:
protein-binding activity modulator
Performance Guarantee
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