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VAMP3 Polyclonal Antibody
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Product Details
OSS00046G-500UG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from mouse VAMP3 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Amount
500 µg
Purification
Ammonium sulfate precipitation
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: VAMP3.
Target Information
Synaptobrevins/VAMPs, syntaxins, and the 25-kDa synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CEB; Cellubrevin; Synaptobrevin-3; unnamed protein product; vamp; VAMP-3; VAMP3; Vesicle-associated membrane protein 3
Gene Aliases: CEB; D130027G05Rik; SYB3; VAMP-3; VAMP3
UniProt ID: (Human) Q9BRV4, (Mouse) P63024, (Rat) P63025
Entrez Gene ID: (Human) 9341, (Mouse) 22319, (Rat) 29528
positive regulation of receptor recycling
protein complex assembly
transport
vesicle fusion
protein transport
vesicle-mediated transport
calcium ion regulated exocytosis
substrate adhesion-dependent cell spreading
SNARE complex assembly
retrograde transport, endosome to Golgi
Golgi to plasma membrane protein transport
negative regulation of secretion by cell
positive regulation of immunoglobulin production
exocytosis
vesicle docking involved in exocytosis
establishment of localization in cell
membrane fusion
protein-containing complex assembly
mucus secretion
cellular response to interferon-gamma
regulation of histamine secretion by mast cell
neurotransmitter secretion
positive regulation of immunoglobulin secretion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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