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Proteintech
VAX2 Polyclonal Antibody
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Product Details
15773-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
VAX2 Fusion Protein Ag8439 (1-290 aa encoded by BC006336)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Amount
40.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MGDGGAERD RGPARRAESG GGGGRCGDRS GAGDLRADGG GHSPTEVAGT SASSPAGSRE SGADSDGQPG PGEADHCRRI LVRDAKGTIR EIVLPKGLDL DRPKRTRTSF TAEQLYRLEM EFQRCQYVVG RERTELARQL NLSETQVKVW FQNRRTKQKK DQSRDLEKRA SSSASEAFAT SNILRLLEQG RLLSVPRAPS LLALTPSLPG LPASHRGTSL GDPRNSSPRL NPLSSASASP PLPPPLPAVC FSSAPLLDLP AGYELGSSAF EPYSWLERKV GSASSCKKAN T (1-290 aa encoded by BC006336)
Target Information
This gene encodes a homeobox protein and is almost exclusively expressed in the ventral portion of the retina during development. In mouse studies, this gene was found to be required for the correct formation of the optic fissure and other aspects of retinal development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Ventral anterior homeobox 2; ventral anterior homeobox containing gene 2; Ventral retina homeodomain protein
Gene Aliases: DRES93; VAX2; Vex
UniProt ID: (Human) Q9UIW0, (Mouse) Q9WTP9, (Rat) Q9JLZ9
Entrez Gene ID: (Human) 25806, (Mouse) 24113, (Rat) 64572
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
chromatin DNA binding
sequence-specific double-stranded DNA binding
sequence-specific DNA binding
homeodomain transcription factor
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
ectoderm development
axonogenesis
central nervous system development
brain development
visual perception
dorsal/ventral axis specification
Wnt signaling pathway
neuron differentiation
forebrain development
camera-type eye development
embryonic eye morphogenesis
retina development in camera-type eye
transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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