Search

  • Contáctenos
  • Orden Rápida

Invitrogen

VCP Polyclonal Antibody

Advanced Verification
View all (32) VCP antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
VCP Polyclonal Antibody

Product Details

PA5-80217

Applications
Tested Dilution
Publications

Western Blot (WB)

0.1-0.5 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

0.5-1 µg/mL
-

Immunohistochemistry (Frozen) (IHC (F))

0.5-1 µg/mL
-

Immunocytochemistry (ICC/IF)

0.5-1 µg/mL
-

Flow Cytometry (Flow)

1-3 µg/1x10^6 cells
-
Product Specifications

Species Reactivity

Human, Mouse, Non-human primate, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human VCP (749-766aa DNDIRKYEMFAQTLQQSR).
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

500 µg/mL

Amount

100 µg

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5mg BSA

Contains

0.01mg sodium azide, 0.05mg thimerosal

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2747331

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Positive Control - WB: human Hela whole cell, human SH-SY5Y whole cell, human MCF-7 whole cell, human A431 whole cell, human K562 whole cell, human HepG2 whole cell, monkey COS-7 whole cell, rat brain tissue, rat lung tissue, rat stomach tissue, rat C6 whole cell, mouse brain tissue, mouse lung tissue, mouse RAW2647 whole cell, human Hela whole cell, human SH-SY5Y whole cell, human MCF-7 whole cell, human A431 whole cell, human HepG2 whole cell, human K562 whole cell, human U87 whole cell, rat brain tissue, rat lung tissue, rat kidney tissue, rat C6 whole cell, mouse brain tissue, mouse lung tissue, mouse kidney tissue, mouse RAW2647 whole cell. IHC: Human Mammary Cancer tissue, Rat Cerebellum tissue, Rat Epinephros tissue, Rat Intestine tissue, mouse intestine tissue IHC-F: Rat Intestine tissue. ICC/IF: A431 cell, K562 cell. Flow: HELA cell.

Target Information

The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: 15S Mg(2+)-ATPase p97 subunit; AAA ATPase p97; homolog of yeast cdc48; Inv protein; or HEL-S-70; p97 atpase; TER ATPase; Transitional endoplasmic reticulum ATPase; unnamed protein product; Valosin-containing protein; VCP

View more View less

Gene Aliases: 3110001E05; CDC48; FTDALS6; HEL-220; HEL-S-70; p97; p97/VCP; TERA; VCP

View more View less

UniProt ID: (Human) P55072, (Mouse) Q01853, (Rat) P46462

View more View less

Entrez Gene ID: (Human) 7415, (Mouse) 269523, (Rat) 116643

View more View less

Function(s)
nucleotide binding RNA binding protein binding ATP binding lipid binding hydrolase activity ATPase activity protein phosphatase binding protein domain specific binding polyubiquitin binding ubiquitin protein ligase binding deubiquitinase activator activity K48-linked polyubiquitin binding MHC class I protein binding identical protein binding ADP binding ubiquitin-like protein ligase binding macromolecular complex binding ubiquitin-dependent protein binding BAT3 complex binding ubiquitin-specific protease binding receptor binding protein complex binding poly(A) RNA binding
Process(es)
DNA repair double-strand break repair ubiquitin-dependent protein catabolic process transport ER to Golgi vesicle-mediated transport activation of cysteine-type endopeptidase activity involved in apoptotic process cellular response to DNA damage stimulus protein ubiquitination protein N-linked glycosylation via asparagine viral genome replication translesion synthesis ER-associated ubiquitin-dependent protein catabolic process retrograde protein transport, ER to cytosol positive regulation of protein complex assembly positive regulation of proteasomal ubiquitin-dependent protein catabolic process protein hexamerization positive regulation of protein catabolic process protein homooligomerization aggresome assembly ER-associated misfolded protein catabolic process positive regulation of protein K63-linked deubiquitination positive regulation of Lys63-specific deubiquitinase activity autophagy I-kappaB kinase/NF-kappaB signaling proteasomal protein catabolic process positive regulation of mitochondrial membrane potential macroautophagy NAD metabolic process endoplasmic reticulum unfolded protein response endosome to lysosome transport via multivesicular body sorting pathway cellular response to heat negative regulation of hippo signaling stress granule disassembly interstrand cross-link repair ERAD pathway regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process establishment of protein localization negative regulation of smoothened signaling pathway ATP metabolic process regulation of synapse organization mitotic spindle disassembly endoplasmic reticulum stress-induced pre-emptive quality control cellular response to misfolded protein flavin adenine dinucleotide catabolic process positive regulation of canonical Wnt signaling pathway autophagosome maturation protein-DNA covalent cross-linking repair negative regulation of protein localization to chromatin cytoplasm protein quality control positive regulation of NIK/NF-kappaB signaling regulation of aerobic respiration cellular response to arsenite ion positive regulation of oxidative phosphorylation regulation of protein localization to chromatin positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process positive regulation of ATP biosynthetic process
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support