Immunogen sequence: LLCGALSELH VPPEWLAPGG KLYNLAKSTH GQLRTDKNYS FPLNNLVCSY DSVKDVLVPD YGMSNLTACN WCHGTSVRKV RGDGSIVYLD G
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 95%.
Acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP. Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Deubiquitinating protein VCIP135; valosin containing protein (p97)/p47 complex interacting protein 1; valosin-containing protein (p97)/p47 complex-interacting protein p135; Valosin-containing protein p97/p47 complex-interacting protein 1; Valosin-containing protein p97/p47 complex-interacting protein p135; VCP/p47 complex-interacting 135-kDa protein
Gene Aliases: DUBA3; KIAA1850; VCIP135; VCPIP1
UniProt ID: (Human) Q96JH7
Entrez Gene ID: (Human) 80124