Keep as concentrated solution.
Predicted reactivity: Mouse (85%), Rat (87%), Rhesus Monkey (99%).
Positive Control: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji, mouse brain.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP. Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Deubiquitinating protein VCIP135; valosin containing protein (p97)/p47 complex interacting protein 1; valosin-containing protein (p97)/p47 complex-interacting protein p135; Valosin-containing protein p97/p47 complex-interacting protein 1; Valosin-containing protein p97/p47 complex-interacting protein p135; VCP/p47 complex-interacting 135-kDa protein
Gene Aliases: 4932442A08; 5730421J18Rik; 5730538E15Rik; DUBA3; KIAA1850; mKIAA1850; VCIP135; VCPIP1