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Invitrogen
VCPIP1 Polyclonal Antibody
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Product Details
PA5-85230
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human VCPIP1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (85%), Rat (87%), Rhesus Monkey (99%).
Positive Control: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji, mouse brain.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP. Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: deubiquitinating protein VCIP135; Deubiquitinating protein VCPIP1; unnamed protein product; Valosin-containing protein p97/p47 complex-interacting protein 1; Valosin-containing protein p97/p47 complex-interacting protein p135; VCP/p47 complex-interacting 135-kDa protein
Gene Aliases: 4932442A08; 5730421J18Rik; 5730538E15Rik; DUBA3; KIAA1850; mKIAA1850; VCIP135; VCPIP1
UniProt ID: (Human) Q96JH7, (Mouse) Q8CDG3
Entrez Gene ID: (Human) 80124, (Mouse) 70675
DNA repair
proteolysis
cellular response to DNA damage stimulus
Golgi organization
endoplasmic reticulum membrane fusion
protein ubiquitination
protein deubiquitination
protein K11-linked deubiquitination
protein K48-linked deubiquitination
Golgi reassembly
protein-DNA covalent cross-linking repair
regulation of protein localization to chromatin
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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