Proteintech

VDAC1/2 Polyclonal Antibody

Product Image Gallery

VDAC1/2 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 10866-1-AP (VDAC1/Porin antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

VDAC1/2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human pancreas using 10866-1-AP (VDAC1 antibody) at dilution of 1:50 (under 40x lens).

VDAC1/2 Antibody in Western Blot (WB) — Mouse kidney tissue were subjected to SDS PAGE followed by western blot with 10866-1-AP (VDAC1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

VDAC1/2 Antibody in Immunoprecipitation (IP) — IP result of anti-VDAC1 (IP:10866-1-AP, 3ug; Detection:10866-1-AP 1:1000) with mouse skeletal muscle tissue lysate 7500ug.

Product Details

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 36 publications 36 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Insect, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

VDAC1/2 Fusion Protein Ag1144

Conjugate

Unconjugated

Form

Liquid

Concentration

0.21 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.1% sodium azide

Storage conditions

-20°C

Product Specific Information

This polyclonal antibody raised against full-length human VDAC1 protein can cross react with VDAC2.

Target Information

This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: B36-VDAC; mVDAC1; mVDAC5; Outer mitochondrial membrane protein porin 1; Outer mitochondrial membrane protein porin 2; Plasmalemmal porin; Porin 31HL; Porin 31HM; rVDAC1; VDAC-1; VDAC-2; VDAC-5; VDAC-6; voltage-dependent anion channel 2; Voltage-dependent anion-selective channel protein 1; Voltage-dependent anion-selective channel protein 2; Voltage-dependent anion-selective channel protein 5; Voltage-dependent anion-selective channel protein 6

Gene Aliases: AL033343; mVDAC2; mVDAC6; POR; PORIN; VDAC; VDAC-1; VDAC1; VDAC2; Vdac5; Vdac6

UniProt ID: (Human) P21796, (Human) P45880, (Mouse) Q60932, (Rat) Q9Z2L0, (Mouse) Q60930, (Rat) P81155

Entrez Gene ID: (Human) 7416, (Human) 7417, (Mouse) 22333, (Rat) 83529, (Mouse) 22334, (Rat) 83531

Molecular Function: voltage-gated ion channel