Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
CL488-10866
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
VDAC1/2 fusion protein Ag1144
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MAVPPTYAD LGKSARDVFT KGYGFGLIKL DLKTKSENGL EFTSSGSANT ETTKVTGSLE TKYRWTEYGL TFTEKWNTDN TLGTEITVED QLARGLKLTF DSSFSPNTGK KNAKIKTGYK REHINLGCDM DFDIAGPSIR GALVLGYEGW LAGYQMNFET AKSRVTQSNF AVGYKTDEFQ LHTNVNDGTE FGGSIYQKVN KKLETAVNLA WTAGNSNTRF GIAAKYQIDP DACFSAKVNN SSLIGLGYTQ TLKPGIKLTL SALLDGKNVN AGGHKLGLGL EFQA
Target Information
This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: B36-VDAC; mVDAC1; mVDAC5; Non-selective voltage-gated ion channel VDAC1; Outer mitochondrial membrane protein porin 1; Outer mitochondrial membrane protein porin 2; Plasmalemmal porin; Porin 31HL; Porin 31HM; rVDAC1; VDAC-1; VDAC-2; VDAC-5; VDAC-6; voltage-dependent anion channel 2; Voltage-dependent anion-selective channel protein 1; Voltage-dependent anion-selective channel protein 2; Voltage-dependent anion-selective channel protein 5; Voltage-dependent anion-selective channel protein 6
Gene Aliases: AL033343; mVDAC2; mVDAC6; POR; PORIN; VDAC; VDAC-1; VDAC1; VDAC2; Vdac5; Vdac6
UniProt ID: (Human) P21796, (Human) P45880, (Mouse) Q60932, (Rat) Q9Z2L0, (Mouse) Q60930, (Rat) P81155
Entrez Gene ID: (Human) 7416, (Human) 7417, (Mouse) 22333, (Rat) 83529, (Mouse) 22334, (Rat) 83531
behavioral fear response
anion transport
mitochondrial calcium ion transport
apoptotic process
neuron-neuron synaptic transmission
learning
viral process
macroautophagy
epithelial cell differentiation
anion transmembrane transport
regulation of mitophagy
regulation of anion transmembrane transport
negative regulation of reactive oxygen species metabolic process
negative regulation of protein polymerization
transmembrane transport
negative regulation of intrinsic apoptotic signaling pathway
transport
ion transport
chemical synaptic transmission
regulation of anion transport
ion transmembrane transport
regulation of ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support