PA5-28106 targets VDAC2 in IF and WB applications and shows reactivity with Human and mouse samples.
The PA5-28106 immunogen is synthetic peptide corresponding to a region within amino acids 233 and 294 of Human VDAC2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants.
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Protein Aliases: Outer mitochondrial membrane protein porin 2; POR; VDAC-2; VDAC-6; voltage-dependent anion channel 2; Voltage-dependent anion-selective channel protein 2; Voltage-dependent anion-selective channel protein 6
Gene Aliases: mVDAC2; mVDAC6; POR; VDAC2; Vdac6