FIGURE: 1 / 5
A suggested positive control is mouse brain tissue lysate.
PA5-21006 can be used with blocking peptide PEP-1120.
VENTX is a member of the Lymphoid-enhancing factor/T-cell factors (LEF1/TCF), which are a high-mobility group of transcriptional factors that play essential roles in cell fate determination during early embryogenesis and ontogenesis. VENTX is a member of the Vent family of homeodomain proteins. It is a novel LEF/TCF-associated transcriptional modulator. VENTX is predominately expressed in hematopoietic cells. VENTX may function as a transcriptional repressor and be involved in mesodermal patterning and hemapoietic stem cell maintenance, and has been suggested to have a potential role in the hematopoietic malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hemopoietic progenitor homeobox protein VENTX2; Homeobox protein VENTX; VENT homeobox homolog; VENT-like homeobox 2; VENT-like homeobox protein 2
Gene Aliases: HPX42B; NA88A; VENTX; VENTX2
UniProt ID: (Human) O95231
Entrez Gene ID: (Human) 27287
Molecular Function: homeodomain transcription factor