Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-96231
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000-1:2,000 | View 1 publication 1 publication |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A recombinant fusion protein containing a sequence corresponding to amino acids 1-525 of human VGAT. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2808033 |
Product Specific Information
Positive Samples: Mouse spinal cord, Mouse brain; Cellular Location: Cytoplasmic vesicle membrane, Multi-pass membrane protein
Target Information
The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles (McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GABA and glycine transporter; GVAT; hVIAAT; mVGAT; mVIAAT; rat UNC-47 homolog; rGVAT; RUNC-47; solute carrier family 32 (GABA vesicular transporter), member 1; Solute carrier family 32 member 1; vasicular inhibitory amino acid transporter 10D; Vesicular GABA and glycine transporter; Vesicular GABA transporter; Vesicular inhibitory amino acid transporter
Gene Aliases: R75019; SLC32A1; VGAT; VIAAT
UniProt ID: (Human) Q9H598, (Rat) O35458, (Mouse) O35633
Entrez Gene ID: (Human) 140679, (Rat) 83612, (Mouse) 22348
amino acid transmembrane transport
neurotransmitter transport
aging
gamma-aminobutyric acid transport
glycine transport
proton transport
sodium ion transmembrane transport
L-alpha-amino acid transmembrane transport
transport
ion transport
neurotransmitter secretion
amine transport
hippocampus development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support