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VGluT3 Polyclonal Antibody
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FIGURE: 1 / 10
VGluT3 Antibody (OSV00047W-100UL) in IHC (P)
IHC-P on paraffin sections of mouse brain (hippocampus). The animal was perfused using Autoperfuser at a pressure of 130 mmHg with 300 mL 4% FA before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions; DAB chromogen: Ca... View More
Product Details
OSV00047W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from mouse VGLUT3 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: VGLUT3.
Target Information
Glucose is fundamental to the metabolism of mammalian cells. Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF-1 induced signaling. GLUT-3 is detectable in a few normal cell type spermatids in testis with active spermatogenesis, placental trophoblast membranes, and neurons in brain. GLUT-3 staining is also detectable in human cancers including those of the ovary, lung, and testis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8; solute carrier family 17 (vesicular glutamate transporter), member 8; Solute carrier family 17 member 8; unnamed protein product; Vesicular glutamate transporter 3; vesicular glutamate transporter-3; VGLUT 3; VGluT3
Gene Aliases: BC042593; DFNA25; SLC17A8; VGLUT3
UniProt ID: (Human) Q8NDX2, (Mouse) Q8BFU8, (Rat) Q7TSF2
Entrez Gene ID: (Human) 246213, (Mouse) 216227, (Rat) 266767
chloride channel activity
L-glutamate transmembrane transporter activity
neurotransmitter transporter activity
sodium:phosphate symporter activity
protein binding
secondary active transmembrane transporter activity
symporter activity
transmembrane transporter activity
L-glutamate uniporter activity
secondary carrier transporter
neural retina development
ion transport
sodium ion transport
phosphate ion transport
chloride transport
neurotransmitter transport
sensory perception of sound
L-glutamate transport
ion transmembrane transport
synaptic transmission, glutamatergic
sodium ion transmembrane transport
sodium-dependent phosphate transport
regulation of synapse structure or activity
regulation of acetylcholine uptake
L-glutamate import
positive regulation of glutamate uptake involved in transmission of nerve impulse
phosphate ion homeostasis
transmembrane transport
cochlea development
neurotransmitter loading into synaptic vesicle
chloride transmembrane transport
transport
L-glutamate transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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