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Product Details
PA5-120172
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500 - 1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50 - 1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 31-170 of human VIP (NP_003372.1). |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.61 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2913744 |
Product Specific Information
Positive test controls include: Rat spinal cord. The target is usually found in the following locations: Secreted.
Target Information
VIP encodes a protein that belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Intestinal peptide PHI-27; Intestinal peptide PHI-42; Intestinal peptide PHM-27; Intestinal peptide PHV-42; MGC13587; PACAP-R-2; Peptide histidine isoleucinamide 27; Peptide histidine methioninamide 27; Peptide histidine valine 42; PHI, peptide histidine isoleucine; prepro-VIP; Vasoactive intestinal peptide; Vasoactive intestinal polypeptide; VIP; VIP peptides
Gene Aliases: PHM27; VIP; vip/phi27
UniProt ID: (Human) P01282, (Rat) P01283, (Mouse) P32648
Entrez Gene ID: (Human) 7432, (Rat) 117064, (Mouse) 22353
Molecular Function:
neuropeptide
positive regulation of endothelial cell proliferation
G-protein coupled receptor signaling pathway
body fluid secretion
learning or memory
positive regulation of cell proliferation
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
regulation of protein localization
negative regulation of apoptotic process
negative regulation of potassium ion transport
positive regulation of protein catabolic process
positive regulation of vasodilation
mRNA stabilization
negative regulation of smooth muscle cell proliferation
regulation of sensory perception of pain
positive regulation of penile erection
prolactin secretion
regulation of signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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