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Invitrogen
VLDLR Polyclonal Antibody
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FIGURE: 1 / 4
VLDLR Antibody (PA5-116116) in IHC (P)
Immunohistochemistry analysis of VLDLR in mouse muscle tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-116116) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Product Details
PA5-116116
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human VLDLR(Accession P98155), corresponding to amino acid residues A122-V172.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total VLDL Receptor.
Target Information
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ35024; unnamed protein product; Very low-density lipoprotein receptor; VLDL receptor; VLDL-R
Gene Aliases: AA408956; AI451093; AW047288; CAMRQ1; CARMQ1; CHRMQ1; VLDL-R; VLDLR; VLDLRCH
UniProt ID: (Human) P98155, (Mouse) P98156
Entrez Gene ID: (Human) 7436, (Mouse) 22359, (Rat) 25696
low-density lipoprotein receptor activity
calcium ion binding
protein binding
very-low-density lipoprotein particle receptor activity
apolipoprotein binding
very-low-density lipoprotein particle binding
cargo receptor activity
reelin receptor activity
calcium-dependent protein binding
glycoprotein binding
glycoprotein transporter activity
protein tyrosine kinase activator activity
apolipoprotein
lipid metabolic process
lipid transport
endocytosis
receptor-mediated endocytosis
signal transduction
nervous system development
memory
steroid metabolic process
cholesterol metabolic process
ventral spinal cord development
glycoprotein transport
very-low-density lipoprotein particle clearance
reelin-mediated signaling pathway
dendrite morphogenesis
regulation of synapse assembly
positive regulation of dendrite development
negative regulation of transcription from RNA polymerase II promoter
transport
positive regulation of protein kinase activity
cellular response to hypoxia
response to hypoxia
cell surface receptor signaling pathway
heart development
response to nutrient
response to hormone
cerebral cortex development
response to lipopolysaccharide
cellular response to insulin stimulus
cellular response to glucose starvation
response to drug
positive regulation of protein tyrosine kinase activity
cellular response to lipopolysaccharide
cellular response to interleukin-1
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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