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Invitrogen
VLDLR Polyclonal Antibody
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FIGURE: 1 / 6
VLDLR Antibody (PA5-25657) in IHC (P)
Immunohistochemistry analysis of VLDLR in paraformaldehyde-fixed, paraffin-embedded human heart tissue sections. Samples were incubated with VLDLR polyclonal antibody (Product # PA5-25657) using a dilution of 1:25 for 1 hours at 37°C followed by an undiluted biotinylated goat polyvalent antibody. Tissue was fixed with formaldehyde and blocked with 3% BSA for 0.5 hour at room temperature; antigen retrieval w... View More
Product Details
PA5-25657
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 484-510 amino acids from the central region of human VLDLR
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with rabbit based on sequence homology.
Target Information
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ35024; Very low-density lipoprotein receptor; VLDL receptor
Gene Aliases: CAMRQ1; CARMQ1; CHRMQ1; VLDL-R; VLDLR; VLDLRCH
UniProt ID: (Human) P98155
Entrez Gene ID: (Human) 7436
glycoprotein binding
low-density lipoprotein receptor activity
calcium ion binding
protein binding
very-low-density lipoprotein particle receptor activity
apolipoprotein binding
very-low-density lipoprotein particle binding
glycoprotein transporter activity
reelin receptor activity
calcium-dependent protein binding
apolipoprotein
negative regulation of transcription from RNA polymerase II promoter
lipid transport
receptor-mediated endocytosis
signal transduction
nervous system development
heart development
response to nutrient
memory
cholesterol metabolic process
ventral spinal cord development
cerebral cortex development
cellular response to insulin stimulus
glycoprotein transport
very-low-density lipoprotein particle clearance
reelin-mediated signaling pathway
cellular response to glucose starvation
response to drug
positive regulation of protein kinase activity
dendrite morphogenesis
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to hypoxia
positive regulation of dendrite development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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