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Osenses
VMAT2 Polyclonal Antibody
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Product Details
OSV00061W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 460-510 of human VMAT2 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The antigen shares 89% identity with rat and mouse sequences.
Specificity of this antibody: VMAT2.
Target Information
VMAT2 is involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. It is a requisite for vesicular amine storage prior to secretion via exocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MGC120477; MGC120478; MGC26538; monoamine neurotransmitter transporter; monoamine transporter; solute carrier family 18 (vesicular monoamine transporter), member 2; solute carrier family 18 (vesicular monoamine), member 2; Solute carrier family 18 member 2; Synaptic vesicular amine transporter; VAT2; vesicle monoamine transporter type 2; vesicle monoamine/H+ antiporter; Vesicular amine transporter 2; Vesicular monoamine transporter 2
Gene Aliases: SLC18A2; SVAT; SVMT; VAT2; VMAT2
UniProt ID: (Human) Q9H3P6
Entrez Gene ID: (Human) 6571
response to amphetamine
serotonin transport
chemical synaptic transmission
neurotransmitter secretion
aging
locomotory behavior
response to herbicide
post-embryonic development
response to zinc ion
aminergic neurotransmitter loading into synaptic vesicle
monoamine transport
dopamine transport
insulin secretion
endocytic recycling
cellular response to drug
sequestering of neurotransmitter
response to cocaine
glucose homeostasis
response to starvation
response to corticosterone
negative regulation of neurotransmitter transport
transmembrane transport
cellular response to ammonium ion
neurotransmitter loading into synaptic vesicle
negative regulation of reactive oxygen species biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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