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Product Details
PA5-102661
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthesized peptide derived from human SLC18A2, corresponding to a region within C-terminal amino acids. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2852058 |
Target Information
VMAT2 is involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. It is a requisite for vesicular amine storage prior to secretion via exocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC120477; MGC120478; MGC26538; monoamine neurotransmitter transporter; Monoamine transporter; solute carrier family 18 (vesicular monoamine transporter), member 2; solute carrier family 18 (vesicular monoamine), member 2; Solute carrier family 18 A2 (vesicular monoamine transporter 2); Solute carrier family 18 member 2; solute carrier family 18, member 2; Synaptic vesicular amine transporter; VAT2; vesicle monoamine transporter type 2; vesicle monoamine/H+ antiporter; Vesicular amine transporter 2; vesicular monoamine transporter 2
Gene Aliases: 1110037L13Rik; 9330105E13; MNAT; SLC18A2; SVAT; SVMT; VAT2; VMAT-2; VMAT2
UniProt ID: (Human) Q05940, (Mouse) Q8BRU6, (Rat) Q01827
Entrez Gene ID: (Human) 6571, (Mouse) 214084, (Rat) 25549
Molecular Function:
secondary carrier transporter
response to amphetamine
serotonin transport
chemical synaptic transmission
neurotransmitter secretion
aging
locomotory behavior
response to herbicide
post-embryonic development
response to zinc ion
aminergic neurotransmitter loading into synaptic vesicle
monoamine transport
dopamine transport
insulin secretion
endocytic recycling
cellular response to drug
sequestering of neurotransmitter
response to cocaine
glucose homeostasis
response to starvation
response to corticosterone
negative regulation of neurotransmitter transport
transmembrane transport
cellular response to ammonium ion
neurotransmitter loading into synaptic vesicle
negative regulation of reactive oxygen species biosynthetic process
transport
neurotransmitter transport
response to toxic substance
organic cation transport
drug transport
obsolete death
ammonium transmembrane transport
drug transmembrane transport
response to metal ion
response to drug
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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