Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MNENIDILET AIKQAAEQGA RIIVTPEDAL YGWKFTRETV FPYLEDIPDP QVNWIPCQDP HRFGHTPVQA RLSCLAKDNS IYVLANLGDK KPCNSRDSTC PPNGYFQYNT NVVYNTEGKL VARYHKYHLY SEPQFNVPEK PELVTFNTAF GRFGIFTCFD IFFYDPGVTL VKDFHVDTIL FPTAWMNVLP LLTAIEFHSA WAMGMGVNLL VANTHHVSLN MTGSGIYAPN GPKVYHYDMK TELGKLLLSE VDSHPLSSLA YPTAVNWNAY ATTIKPFPVQ KNTFRGFISR DGFNFTELFE NAGNLTVCQK ELCCHLSYRM LQKEENEVYV LGAFTGLHGR RRREYWQVCT MLKCKTTNLT TCGRPVETAS TRFEMFSLSG TFGTEYVFPE VLLTEIHLSP GKFEVLKDGR LVNKNGSSGP ILTVSLFGRW YTKDSLYSSC GTSNSAITYL LIFILLMIIA LQNIVML
This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Glycosylphosphatidyl inositol-anchored protein GPI-80; pantetheinase; Pantetheine hydrolase VNN2; Protein FOAP-4; Vanin-2; Vannin 2; Vascular non-inflammatory molecule 2
Gene Aliases: FOAP-4; GPI-80; VNN2
UniProt ID: (Human) O95498
Entrez Gene ID: (Human) 8875
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