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VPAC2R Polyclonal Antibody
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Product Details
BS-0197R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from rat VIP receptor II, amino acids 81-170.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The Vasoactive Intestinal Polypeptide Receptor 2 (VPAC2) is a member of a family of three G-protein coupled receptors which mediate VIP (vasoactive intestinal peptide) and PACAP (pituitary adenlyate cyclase activating peptide) function in a variety of tissues. Together, the VPAC1 and VPAC2 receptors compose a subtype of the VIP receptor. Expression of the VIP and PACAP receptors has been linked to the presence of human tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Helodermin-preferring VIP receptor; human VIP2 receptor was previously called 'helodermin-preferring VIP receptor'; transmembrane domains are located at positions: 637-696; 772-844; 880-948; 1003-1071; 1147-1209; 1243-1302.; Potential glycosylation sites are located at :334-336; 424-426; 436; PACAP type III receptor; Pacap type-3; PACAP-R-3; PACAP-R3; PACAP3; PACAPR-3; Pituitary adenylate cyclase-activating polypeptide type III receptor; Pvr3; SCZD16; tcag7.970; unnamed protein product; Vasoactive intestinal polypeptide receptor 2; vasopressive intestinal peptide receptor 2; VIP and PACAP receptor 2; VIP receptor subtype 2; Vip type-2 receptor; VIP-R-2; Vip-r2; Vip2 receptor; VPAC2 receptor; VPAC2R
Gene Aliases: C16DUPq36.3; DUP7q36.3; PACAP-R-3; PACAP-R3; VIP-R-2; Vip2; VIP2R; VIPR2; VPAC2; VPAC2R; VPCAP2R
UniProt ID: (Human) P41587, (Rat) P35000, (Mouse) P41588
Entrez Gene ID: (Human) 7434, (Rat) 29555, (Mouse) 22355
pituitary adenylate cyclase-activating polypeptide receptor activity
transmembrane signaling receptor activity
G-protein coupled receptor activity
vasoactive intestinal polypeptide receptor activity
G-protein coupled peptide receptor activity
peptide hormone binding
signal transducer activity
transmembrane signal receptor
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
cell-cell signaling
activation of adenylate cyclase activity
negative regulation of smooth muscle cell proliferation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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