|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 120 and 182 of Human VPS29|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 40% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
PA5-28117 targets VPS29 in WB applications and shows reactivity with Human samples.
The PA5-28117 immunogen is synthetic peptide corresponding to a region within amino acids 120 and 182 of Human VPS29.
This gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms, and usage of multiple polyadenylation sites have been found for this gene.
DC15; hVPS29; PEP11; PEP11 homolog; retromer protein; vacuolar protein sorting 29 homolog; vacuolar protein sorting-associated protein 29; vacuolar sorting protein VPS29/PEP11; vesicle protein sorting 29; VPS29 retromer complex component; x 007 protein
DC15; DC7; MDS007; PEP11; VPS29