Proteintech

VPS33A Polyclonal Antibody

FIGURE: 1 / 5

VPS33A Antibody (16896-1-AP) in WB

Human cerebellum tissue were subjected to SDS PAGE followed by western blot with 16896-1-AP (VPS33A antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

VPS33A Antibody in Immunoprecipitation (IP)

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Product Details

16896-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 6 publications 6 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

VPS33A Fusion Protein Ag10422 (246-596 aa encoded by BC016617)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.18 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: YEGLIDEIY GIQNSYVKLP PEKFAPKKQG DGGKDLPTEA KKLQLNSAEE LYAEIRDKNF NAVGSVLSKK AKIISAAFEE RHNAKTVGEI KQFVSQLPHM QAARGSLANH TSIAELIKDV TTSEDFFDKL TVEQEFMSGI DTDKVNNYIE DCIAQKHSLI KVLRLVCLQS VCNSGLKQKV LDYYKREILQ TYGYEHILTL HNLEKAGLLK PQTGGRNNYP TIRKTLRLWM DDVNEQNPTD ISYVYSGYAP LSVRLAQLLS RPGWRSIEEV LRILPGPHFE ERQPLPTGLQ KKRQPGENRV TLIFFLGGVT FAEIAALRFL SQLEDGGTEY VIATTKLMNG TSWIEALMEK PF (246-596 aa encoded by BC016617)

Target Information

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and it encodes a protein similar to the yeast class C Vps33 protein. The mammalian class C VPS proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.

Autophagy

Zheng W,Chen Q,Liu H,Zeng L,Zhou Y,Liu X,Bai Y,Zhang J,Pan Y,Shao C

Wed Mar 01 00:00:00 EST 2023

Consecutive functions of small GTPases guide HOPS-mediated tethering of late endosomes and lysosomes.

Cell reports

Schleinitz A,Pöttgen LA,Keren-Kaplan T,Pu J,Saftig P,Bonifacino JS,Haas A,Jeschke A

Tue Jan 31 00:00:00 EST 2023

Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defense.

Cell reports

Fernbach S,Spieler EE,Busnadiego I,Karakus U,Lkharrazi A,Stertz S,Hale BG

Tue Mar 22 00:00:00 EDT 2022

Mystery of methamphetamine-induced autophagosome accumulation in hippocampal neurons: loss of syntaxin 17 in defects of dynein-dynactin driving and autophagosome-late endosome/lysosome fusion.

Archives of toxicology

Xu H,Zhu Y,Chen X,Yang T,Wang X,Song X,Xie X,Hu M,Jiang L,Cheng J,Gao R,Wang J

Fri Oct 01 00:00:00 EDT 2021

Acetylation of STX17 (syntaxin 17) controls autophagosome maturation.

Autophagy

Shen Q,Shi Y,Liu J,Su H,Huang J,Zhang Y,Peng C,Zhou T,Sun Q,Wan W,Liu W

Sat May 01 00:00:00 EDT 2021

The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes.

The Journal of cell biology

Marwaha R,Arya SB,Jagga D,Kaur H,Tuli A,Sharma M

Mon Apr 03 00:00:00 EDT 2017

The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes.

The Journal of cell biology

Marwaha R,Arya SB,Jagga D,Kaur H,Tuli A,Sharma M

Mon Apr 03 00:00:00 EDT 2017

Salmonella exploits the host endolysosomal tethering factor HOPS complex to promote its intravacuolar replication.

PLoS pathogens

Sindhwani A,Arya SB,Kaur H,Jagga D,Tuli A,Sharma M

Sun Oct 01 00:00:00 EDT 2017

Salmonella exploits the host endolysosomal tethering factor HOPS complex to promote its intravacuolar replication.

PLoS pathogens

Sindhwani A,Arya SB,Kaur H,Jagga D,Tuli A,Sharma M

Sun Oct 01 00:00:00 EDT 2017

The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes.

Journal of cell science

Khatter D,Raina VB,Dwivedi D,Sindhwani A,Bahl S,Sharma M

Fri May 01 00:00:00 EDT 2015

The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes.

Journal of cell science

Khatter D,Raina VB,Dwivedi D,Sindhwani A,Bahl S,Sharma M

Fri May 01 00:00:00 EDT 2015

Bioinformatics

Protein Aliases: buff; hVPS33A; vacuolar protein sorting 33 homolog A; vacuolar protein sorting 33A; vacuolar protein sorting protein 33a; Vacuolar protein sorting-associated protein 33A; vacuolar sorting protein 33a; VPS33A CORVET/HOPS core subunit

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Gene Aliases: 3830421M04Rik; AI503300; AW048546; AW554476; Bf; Buff; r-Vps33a; VPS33A

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UniProt ID: (Human) Q96AX1, (Mouse) Q9D2N9

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Entrez Gene ID: (Human) 65082, (Mouse) 77573, (Rat) 65081

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Function(s)

protein binding protein complex binding membrane trafficking regulatory protein

Process(es)

vesicle docking involved in exocytosis endosome to lysosome transport protein transport vesicle-mediated transport platelet formation melanosome localization lysosome localization regulation of developmental pigmentation autophagosome maturation transport pigmentation biological_process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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VPS33A Polyclonal Antibody

VPS33A Antibody (16896-1-AP) in WB

Product Details

16896-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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