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Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
0.04-0.4 µg/mL | - |
Immunohistochemistry (IHC) |
1:200-1:500 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human VPS45 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.3 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2649473 |
Immunogen sequence: LLNQWTYQAM VHELLGINNN RIDLSRVPGI SKDLREVVLS AENDEFYANN MYLNFAEIGS NIKNLMEDFQ KKKPKEQQKL ESIADMKAFV ENYPQFK
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: h-VPS45; HGNC:14579; hlVps45; leucocyte vacuolar protein sorting 45; RP11-458I7.2; vacuolar protein sorting 45A; Vacuolar protein sorting-associated protein 45
Gene Aliases: H1; H1VPS45; SCN5; VPS45; VPS45A; VPS45B; VPS54A; VSP45; VSP45A
UniProt ID: (Human) Q9NRW7
Entrez Gene ID: (Human) 11311
Molecular Function:
membrane trafficking regulatory protein
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