This antibody is predicted to react with mouse and rat based on sequence homology.
This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARE1; dJ1033B10.5; RP5-1033B10; SAC2; SAC2 suppressor of actin mutations 2-like protein; SACM2L; vacuolar protein sorting 52 homolog; Vacuolar protein sorting-associated protein 52 homolog; VPS52 GARP complex subunit
Gene Aliases: ARE1; dJ1033B10.5; SAC2; SACM2L; VPS52
UniProt ID: (Human) Q8N1B4
Entrez Gene ID: (Human) 6293
Molecular Function: membrane traffic protein