Immunogen sequence: KAAQAGRQSS AKRHLAEQFA VGEIITDMAK KEWKVGLPIG QGGFGCIYLA DMNSSESVGS DAPCVVKVEP SDNGPLFTEL KFYQRAAKPE QIQKWIRTRK LKYLGVPKYW GSGLHDKNGK SYRFMIMDRF GSDLQKI
Human vaccinia-related kinase 1 (VRK1) is a new kinase related to a poxvirus kinase, and more distantly to the casein kinase 1 family. VRK1 shows strong autophosphorylating activity in several Ser and Thr residues. VRK has also been found to be an upstream regulator of p53 that belongs to a new signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Serine/threonine-protein kinase VRK1; vaccinia virus B1R-related kinase 1; Vaccinia-related kinase 1
Gene Aliases: PCH1; PCH1A; VRK1
UniProt ID: (Human) Q99986
Entrez Gene ID: (Human) 7443