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Proteintech
VSX2 Polyclonal Antibody
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Product Details
25825-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
VSX2 Fusion Protein Ag23035 (1-147 aa encoded by BC128153)
Conjugate
Form
Liquid
Concentration
0.34 mg/mL
Amount
51 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MTGKAGEAL SKPKSETVAK STSGGAPARC TGFGIQEILG LNKEPPSSHP RAALDGLAPG HLLAARSVLS PAGVGGMGLL GPGGLPGFYT QPTFLEVLSD PQSVHLQPLG RASGPLDTSQ TASSDSEDVS SSDRKMSKSA LNQTKKRK (1-147 aa encoded by BC128153)
Target Information
CHX10 encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C. elegans ceh-10 homeo domain containing homolog; ceh-10 homeo domain containing homolog; Ceh-10 homeodomain-containing homolog; homeobox protein; Homeobox protein CHX10; ocular retardation; Visual system homeobox 2
Gene Aliases: CHX10; Hox-10; HOX10; MCOP2; MCOPCB3; or; RET1; VSX2
UniProt ID: (Human) P58304, (Mouse) Q61412
Entrez Gene ID: (Human) 338917, (Mouse) 12677
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
protein binding
sequence-specific double-stranded DNA binding
sequence-specific DNA binding
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
neuroblast proliferation
negative regulation of neuroblast proliferation
visual perception
cell proliferation
positive regulation of cell proliferation
central nervous system neuron differentiation
camera-type eye development
cell fate commitment
positive regulation of transcription from RNA polymerase II promoter
retinal bipolar neuron differentiation
retina morphogenesis in camera-type eye
transcription, DNA-templated
multicellular organism development
negative regulation of cell proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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