V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non- conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: SNARE Vti1a-beta protein; vesicle transport through interaction with t-SNAREs 1 homolog; Vesicle transport through interaction with t-SNAREs homolog 1A; Vesicle transport v-SNARE protein Vti1-like 2; Vti1-rp2
Gene Aliases: 1110014F16Rik; 1110018K19Rik; 4921537J05Rik; MMDS3; MVti1; MVti1a; Vti1; Vti1-rp2; VTI1A; Vti1l2; VTI1RP2