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VWF Antibody (BS-4754R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded mouse brain; Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20min; Antibody incubation with VWF Polyclonal Antibody (bs-4754R) at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining.
Product Details
BS-4754R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human VWF/von Willebrand antigen 2, amino acids 351-450.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Von Willebrand factor (vWf) is a series of self-aggregated structures, all derived from common glycoprotein subunits, synthesized in endothelial cells and megakaryocytes. The molecular mass of the monomeric vWf unit is 225 kDa. vWf binds to circulating factor VIIIc (antihemophilic factor), hereby stabilizing the latter thus being an important factor in the normal primary haemostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coagulation Factor VIII; coagulation factor VIII VWF; factor viii related antigen; von Willebrand Disease (vWD); von Willebrand factor; vWF; vwf {ECO:0000312|EMBL:CAB37852.1}
Gene Aliases: 6820430P06Rik; AI551257; B130011O06Rik; C630030D09; F8VWF; VWD; VWF
UniProt ID: (Human) P04275, (Mouse) Q8CIZ8
Entrez Gene ID: (Human) 7450, (Mouse) 22371, (Rat) 116669
platelet degranulation
cell adhesion
blood coagulation
blood coagulation, intrinsic pathway
hemostasis
response to wounding
platelet activation
extracellular matrix organization
cell-substrate adhesion
response to immobilization stress
protein homooligomerization
liver development
placenta development
tissue regeneration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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