This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Recommended positive controls: A431, H1299, HepG2, mouse kidney.
Predicted reactivity: Mouse (89%), Rat (89%), Bovine (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Villin is part of cytoskeleton associated with the microvillar actin core bundle of gastrointestinal and renal brush border. It can interact with actin in a Ca2+ and phosphoinositide-regulated manner. Villin is a very specific marker for adenocarcinomas of the gastrointestinal tract and the pancreas. It is also expressed in some Merkel cell tumor and adenocarcinoma of the lung, prostate, ovarian and kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: OTTHUMP00000207159; Villin-1
Gene Aliases: D2S1471; VIL; VIL1
Molecular Function: non-motor actin binding protein