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Product Details
13796-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
WBSCR16 Fusion Protein Ag4619 (1-350 aa encoded by BC032712)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MALVALVAG ARLGRRLSGP GLGRGHWTAA GRSRSRREAA EAEAEVPVVQ YVGERAARAD RVFVWGFSFS GALGVPSFVV PSSGPGPRAG ARPRRRIQPV PYRLELDQKI SSAACGYGFT LLSSKTADVT KVWGMGLNKD SQLGFHRSRK DKTRGYEYVL EPSPVSLPLD RPQETRVLQV SCGRAHSLVL TDREGVFSMG NNSYGQCGRK VVENEIYSES HRVHRMQDFD GQVVQVACGQ DHSLFLTDKG EVYSCGWGAD GQTGLGHYNI TSSPTKLGGD LAGVNVIQVA TYGDCCLAVS ADGGLFGWGN SEYLQLASVT DSTQVNVPRC LHFSGVGKVR QAACGGTGCA V (1-350 aa encoded by BC032712)
Target Information
Guanine nucleotide exchange factor (GEF) for mitochondrial dynamin-related GTPase OPA1. Activates OPA1, by exchanging bound GDP for free GTP, and drives OPA1 and MFN1-dependent mitochondrial fusion. Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: RCC1-like G exchanging factor-like protein; RCC1-like protein; Williams-Beuren syndrome chromosomal region 16 protein; Williams-Beuren syndrome chromosome region 16
Gene Aliases: RCC1L; WBSCR16
UniProt ID: (Human) Q96I51
Entrez Gene ID: (Human) 81554
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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