PA5-31388 targets WDR19 in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-31388 immunogen is recombinant fragment corresponding to a region within amino acids 33 and 296 of Human WDR19.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains six WD repeats, a clathrin heavy-chain repeat, and three transmembrane domains. This gene is conserved from C. elegans to human. It may participate in androgen-regulated signaling mechanisms or in the vesicular trafficking of androgen-regulated secretory processes. Alternatively spliced transcript variants encoding distinct isoforms have been reported but the full-length nature of one of these variants has not been defined.
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Protein Aliases: ATD5; CED4; DYF-2; IFT144; Intraflagellar transport 144 homolog; NPHP13; ORF26; Oseg6; PWDMP; WD repeat membrane protein PWDMP; WD repeat-containing protein 19
Gene Aliases: ATD5; C330027H04Rik; CED4; D330023L08Rik; DYF-2; DYF2; IFT144; KIAA1638; mKIAA1638; NPHP13; ORF26; Oseg6; PWDMP; SRTD5; WDR19