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Product Details
PA5-58860
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
RRID
Product Specific Information
Immunogen sequence: TGADYIVKIF DRHGQKRSEI NLPGNCVAMD WDKDGDVLAV IAEKSSCIYL WDANTNKTSQ LDNGMRDQMS FLLWSKVGSF LAVGTVKG
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 93%.
Target Information
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains six WD repeats, a clathrin heavy-chain repeat, and three transmembrane domains. This gene is conserved from C. elegans to human. It may participate in androgen-regulated signaling mechanisms or in the vesicular trafficking of androgen-regulated secretory processes. Alternatively spliced transcript variants encoding distinct isoforms have been reported but the full-length nature of one of these variants has not been defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Intraflagellar transport 144 homolog; WD repeat membrane protein PWDMP; WD repeat-containing protein 19
Gene Aliases: ATD5; CED4; DYF-2; IFT144; KIAA1638; NPHP13; ORF26; Oseg6; PWDMP; SRTD5; WDR19
UniProt ID: (Human) Q8NEZ3
Entrez Gene ID: (Human) 57728
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