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          • Primary Antibodies ›
          • WDR5 Antibodies

          Bethyl Laboratories

          WDR5 Polyclonal Antibody

          View all (25) WDR5 antibodies

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          Cite WDR5 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          WDR5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          WDR5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          WDR5 Antibody (IHC-00681) in IHC (P)

          Detection of mouse WDR5 by immunohistochemistry. Sample: FFPE section of mouse renal cell carcinoma. Antibody: Affinity purified rabbit anti-WDR5 (Product # IHC-00681) used at a dilution of 1:250 Detection: DAB. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          WDR5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          WDR5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          WDR5 Polyclonal Antibody

          Product Details

          IHC-00681

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (IHC)

          1:100-1:500
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Region between residue 50 and 100 of Human WD repeat domain 5.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.25 mg/mL

          Amount

          25 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          TBS, pH 7.0 to 8.0, with 0.1% BSA

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          The recommended shelf life for this product is 1 year from date of receipt.

          Based on 100% sequence identity, this antibody is predicted to react with Rat, D. melanogaster, Zebrafish, X. laevis, X. tropicalis, Chicken, Turkey, Bovine, Dog, Horse, Guinea pig_10141, Pig and Panda

          Target Information

          Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: BMP-2-induced gene 3 kb; BMP2-induced 3-kb gene protein; cilia and flagella associated protein 89; SWD3, Set1c WD40 repeat protein, homolog; unnamed protein product; WD repeat-containing protein 5; WD repeat-containing protein BIG-3

          View more View less

          Gene Aliases: 2410008O07Rik; AA408785; AA960360; Big; BIG-3; BIG3; CFAP89; SWD3; WDR5

          View more View less

          UniProt ID: (Human) P61964, (Mouse) P61965

          View more View less

          Entrez Gene ID: (Human) 11091, (Mouse) 140858

          View more View less

          Function(s)
          protein binding histone binding histone methyltransferase activity (H3-K4 specific) histone H3Q5ser reader activity histone H3K4me1 reader activity histone acetyltransferase activity (H4-K5 specific) histone acetyltransferase activity (H4-K8 specific) histone acetyltransferase activity (H4-K16 specific)
          Process(es)
          skeletal system development transcription, DNA-templated regulation of transcription, DNA-templated chromatin modification neuron projection development positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter histone H3 acetylation histone H4-K5 acetylation histone H4-K8 acetylation histone H4-K16 acetylation histone H3-K4 methylation negative regulation of transcription from RNA polymerase II promoter gluconeogenesis chromatin organization regulation of transcription from RNA polymerase II promoter positive regulation of gluconeogenesis positive regulation of gene expression, epigenetic positive regulation of transcription, DNA-templated regulation of embryonic development regulation of cell division regulation of cell cycle
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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