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Abnova
WDR61 Polyclonal Antibody, MaxPab™
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Product Details
H00080349-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
WDR61 (NP_079510.1, 1 a.a. approximately 305 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MTNQYGILFK QEQAHDDAIW SVAWGTNKKE NSETVVTGSL DDLVKVWKWR DERLDLQWSL EGHQLGVVSV DISHTLPIAA SSSLDAHIRL WDLENGKQIK SIDAGPVDAW TLAFSPDSQY LATGTHVGKV NIFGVESGKK EYSLDTRGKF ILSIAYSPDG KYLASGAIDG IINIFDIATG KLLHTLEGHA MPIRSLTFSP DSQLLVTASD DGYIKIYDVQ HANLAGTLSG HASWVLNVAF CPDDTHFVSS SSDKSVKVWD VGTRTCVHTF FDHQDQVWGV KYNGNGSKIV SVGDDQEIHI YDCPI
Target Information
SKI8 is a component of the PAF and SKI complex which is composed of SKI2, SKI3 and SKI8. These are involved in transcriptional regulation and events downstream of RNA synthesis. Interaction of the SKI complex with SKI7 links the SKI complex to the exosome in order to perform mRNA degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GPB; meiotic recombination protein REC14; Meiotic recombination REC14 protein homolog; REC14; recombination protein REC14; SKI complex component SKI8; Ski complex subunit Rec14; Ski8; SKI8 homolog; SKI8 subunit of superkiller complex protein; Superkiller complex protein 8; unnamed protein product; WD repeat domain 61; WD repeat-containing protein 61
Gene Aliases: 2700038L12Rik; 2810418I05Rik; REC14; SKI8; SKIC8; WDR61
UniProt ID: (Human) Q9GZS3, (Mouse) Q9ERF3
Entrez Gene ID: (Human) 80349, (Mouse) 66317
transcription elongation from RNA polymerase II promoter
Wnt signaling pathway
negative regulation of myeloid cell differentiation
nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
rescue of stalled ribosome
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of histone methylation
positive regulation of transcription elongation from RNA polymerase II promoter
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
positive regulation of transcription from RNA polymerase II promoter
positive regulation of histone H3-K4 methylation
histone H3-K4 trimethylation
positive regulation of histone H3-K79 methylation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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