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Invitrogen
WDR61 Polyclonal Antibody
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FIGURE: 1 / 3
WDR61 Antibody (PA5-30833) in ICC/IF
WDR61 Polyclonal Antibody detects WDR61 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: WDR61 protein stained by WDR61 Polyclonal Antibody (Product # PA5-30833) diluted at 1:500. Blue: Hoechst 33342 staining.
Product Details
PA5-30833
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human WDR61. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.6 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: HepG2, mouse stomach.
Predicted reactivity: Mouse (98%), Rat (97%), Zebrafish (90%), Xenopus laevis (89%), Chicken (94%), Rhesus Monkey (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
SKI8 is a component of the PAF and SKI complex which is composed of SKI2, SKI3 and SKI8. These are involved in transcriptional regulation and events downstream of RNA synthesis. Interaction of the SKI complex with SKI7 links the SKI complex to the exosome in order to perform mRNA degradation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GPB; meiotic recombination protein REC14; Meiotic recombination REC14 protein homolog; REC14; recombination protein REC14; SKI complex component SKI8; Ski complex subunit Rec14; Ski8; SKI8 homolog; SKI8 subunit of superkiller complex protein; Superkiller complex protein 8; unnamed protein product; WD repeat domain 61; WD repeat-containing protein 61
Gene Aliases: 2700038L12Rik; 2810418I05Rik; REC14; SKI8; SKIC8; WDR61
UniProt ID: (Human) Q9GZS3, (Mouse) Q9ERF3
Entrez Gene ID: (Human) 80349, (Mouse) 66317
transcription elongation from RNA polymerase II promoter
Wnt signaling pathway
negative regulation of myeloid cell differentiation
nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
rescue of stalled ribosome
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of histone methylation
positive regulation of transcription elongation from RNA polymerase II promoter
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
positive regulation of transcription from RNA polymerase II promoter
positive regulation of histone H3-K4 methylation
histone H3-K4 trimethylation
positive regulation of histone H3-K79 methylation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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